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22 Smilax Vine Rd, Bluffton, SC 29910
22 Smilax Vine Rd, Bluffton, SC 29910
22 Smilax Vine Rd, Bluffton, SC 29910
22 Smilax Vine Rd, Bluffton, SC 29910
22 Smilax Vine Rd, Bluffton, SC 29910
22 Smilax Vine Rd, Bluffton, SC 29910
22 Smilax Vine Rd, Bluffton, SC 29910

22 Smilax Vine Rd Bluffton, SC 29910

$2,195,000

ACTIVE
Beds
Baths
0
Sqft
Acres
2.21
Year
Days on Site
40 Days
Property Type
Land
Sub Type
Unimproved Land
Date Listed
Sep 21, 2026

Description of 22 Smilax Vine Rd, Bluffton, SC 29910

Listing details for 22 Smilax Vine Rd, Bluffton, SC 29910 : Set wіthin the hіghlу sοught‐аfter Mау Rіver Forest neighborhοod οf Palmetto Bluff, 22 Smilax Vine Road presents a rare opportunity to create a custom Lowcountry retreat on an exceptional 2.21-acre homesite. Tucked away on a quiet cul-de-sac and surrounded by protected maritime forest, the homesite enjoys a remarkable sense of privacy while opening to beautiful views of the 16th fairway of the Jack Nicklaus Signature Golf Course. The generous acreage provides an inspiring canvas for a thoughtfully designed residence, with the golf course setting creating a picturesque backdrop and an opportunity to embrace expansive outdoor living. Surrounded by the distinctive landscape of May River Forest, the homesite captures the essence of Palmetto Bluff-where architecture and nature are thoughtfully intertwined. Life at Palmetto Bluff is defined by an extraordinary connection to nature and an unparalleled collection of amenities. Miles of walking and biking trails wind through forests and along waterways, while the community offers championship golf, equestrian facilities, fitness and wellness experiences, boating and river access, restaurants, shops, and an abundance of outdoor pursuits. From quiet mornings surrounded by nature to afternoons on the river and evenings gathered with family, Palmetto Bluff offers an enduring Lowcountry lifestyle unlike any other. With its combination of 2.21 acres, golf course views, mature natural surroundings, and coveted May River Forest location, 22 Smilax Vine Road represents an exceptional opportunity to create a one-of-a-kind Lowcountry legacy property-one thoughtfully designed for both the beauty of today and the generations to come.
Listing Updated : 10-15-2026 at 10:02 AM EDT

Keller Williams Realty | Sheri Nixon Team | Middleton Futures, LLC | We do not attempt to independently verify the currency, completeness, accuracy or authenticity of the data contained herein. All area measurements and calculations are approximate and should be independently verified. Data may be subject to transcription and transmission errors. Accordingly, the data is provided on an “as is” “as available” basis only and may not reflect all real estate activity in the market”. © 2026 REsides, Inc. All rights reserved. Certain information contained herein is derived from information, which is the licensed property of, and copyrighted by, REsides, Inc.

Listing Provided By

Bryan Byrne, 843-247-3374, Palmetto Bluff Real Estate Co

Source

Reside MLS, MLS#: 513047

For more information on this listing contact us at 854-540-1635
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Location of 22 Smilax Vine Rd, Bluffton, SC 29910

Streetview of 22 Smilax Vine Rd, Bluffton, SC 29910

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For more information on this listing contact us at 854-540-1635
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For more information on this listing contact us at 854-540-1635